Across TCGA pan-cancer cohorts, PIMREGP4 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of PIMREGP4’s most consistent transcriptional readouts.
The strongest signal is observed in stomach adenocarcinoma (STAD), where PIMREGP4 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types PIMREGP4 is over-expressed in tumor, although a few such as PAAD show the opposite, repressed pattern.
STAD, PAAD, and BRCA are the cancer types where PIMREGP4 tumor–normal differential expression is most reproducible.