Across TCGA patient cohorts, PIM3 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,887 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PIM3-associated proteins across cancer lineages are PACSIN2, SCO2, and STIM1_S257. Each is linked with PIM3 in more than 3 cancer types. Because this analysis shows association rather than direction, both PIM3-to-partner and partner-to-PIM3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PIM3→partner) and Y-score (partner→PIM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PACSIN2 →	+0.443	+0.868	.004	<.001	3	4
OV	SCO2 →	+0.458	+0.940	<.001	<.001	3	4
BRCA	STIM1_S257 →	+1.142	+0.810	<.001	<.001	3	3
OV	TRABD →	+0.632	+0.757	.001	.003	3	3
OV	UBL4A_S90 →	-0.887	-0.991	.003	.004	3	3
COAD	NUP50 →	+0.252	+0.599	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,887 associations by consensus.

Exploration

PIM3 survival (RNA) · tumor vs normal (RNA) · all PIM3 data types