Across TCGA patient cohorts, PIM3 protein abundance is significantly associated with the RNA expression of many other genes, with 125 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible PIM3-associated genes across cancer lineages are MOGS, F2RL3, and HTR2B. Each is linked with PIM3 in more than 1 cancer types. Because this analysis shows association rather than direction, both PIM3-to-partner and partner-to-PIM3 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PIM3→partner) and Y-score (partner→PIM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	MOGS →	+0.467	+1.831	.001	.001	3	1
PDAC	F2RL3 →	+0.678	+1.831	.005	.001	3	1
PDAC	HTR2B →	+0.948	+1.831	.002	.001	3	1
PDAC	FRS3 →	+0.707	+2.429	<.001	.003	3	1
PDAC	SERF2 →	+0.954	+2.663	.005	.005	3	1
PDAC	NOL3 →	+0.645	+1.800	.006	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 125 associations by consensus.

Exploration

PIM3 survival (RNA) · tumor vs normal (RNA) · all PIM3 data types