PILRA

Across TCGA patient cohorts, PILRA protein abundance is significantly associated with the RNA expression of many other genes, with 7,492 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PILRA-associated genes across cancer lineages are FCGR1A, VSIG4, and FCER1G. Each is linked with PILRA in more than 5 cancer types. Because this analysis shows association rather than direction, both PILRA-to-partner and partner-to-PILRA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PILRA versus FCGR1A in CCRCC, with a Pearson correlation of 0.70.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PILRA→partner) and Y-score (partner→PILRA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	FCGR1A →	+2.078	+2.800	.003	<.001	3	6
CCRCC	VSIG4 →	+1.647	+1.731	.002	.002	3	6
CCRCC	FCER1G →	+0.992	+1.618	.003	.004	3	6
GBM	CD14 →	+1.654	+0.881	<.001	<.001	3	6
GBM	SIRPB2 →	+1.059	+0.745	<.001	<.001	3	6
GBM	LINC01094 →	+1.019	+0.921	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,492 associations by consensus.

PILRA vs FCGR1A — CCRCC

Explore this scatter interactively →