PILRA

Across TCGA cell cohorts, PILRA RNA expression is significantly associated with the go_rna of many other GO terms, with 2,825 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PILRA-associated GO terms across cancer lineages are Positive regulation of toll-like receptor signaling pathway, Activation of transmembrane receptor protein tyrosine kinase activity, and Cilium-dependent cell motility. Each is linked with PILRA in more than 9 cancer types. Because this analysis shows association rather than direction, both PILRA-to-partner and partner-to-PILRA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of toll-like receptor signaling pathway grouped by PILRA-low versus PILRA-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PILRA→partner) and Y-score (partner→PILRA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Positive regulation of toll-like receptor signaling pathway →	+0.139	+1.400	.003	.001	3	10
OESOPHAGUS	Activation of transmembrane receptor protein tyrosine kinase activity →	+0.880	+1.755	.006	<.001	3	9
LUNG_NSCLC_LUAD	Cilium-dependent cell motility →	-0.055	-0.728	<.001	<.001	3	9
LUNG_NSCLC_LUSC	Protein sumoylation →	+0.067	+1.355	<.001	<.001	3	9
LUNG_SCLC	Peptidyl-lysine modification →	+0.045	+0.796	.001	.001	3	9
BONE	Nucleic acid catabolic process →	+0.045	+0.671	<.001	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,825 associations by consensus.

Positive regulation of toll-like receptor signaling pathway by PILRA expression — OESOPHAGUS

Explore this box plot interactively →