PILRA

Across TCGA cell cohorts, PILRA mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PILRA-associated genes across cancer lineages are OC90, TLE7, and PRAMEF20. Each is linked with PILRA in more than 1 cancer types. Because this analysis shows association rather than direction, both PILRA-to-partner and partner-to-PILRA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OC90 grouped by PILRA-low versus PILRA-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PILRA→partner) and Y-score (partner→PILRA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OC90 →	+0.013	+5.201	<.001	.006	3	1
BLOOD_Leukemia	TLE7 →	+0.022	+5.969	<.001	.001	3	1
LARGE_INTESTINE	PRAMEF20 →	+0.015	+5.022	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

OC90 by PILRA expression — BLOOD_Leukemia

Explore this box plot interactively →