PILRA

Across TCGA cell cohorts, PILRA mutation is significantly associated with the mutation status of many other genes, with 1,883 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PILRA-associated genes across cancer lineages are TRAF7, IPO4, and PALB2. Each is linked with PILRA in more than 2 cancer types. Because this analysis shows association rather than direction, both PILRA-to-partner and partner-to-PILRA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRAF7 grouped by PILRA-low versus PILRA-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PILRA→partner) and Y-score (partner→PILRA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	TRAF7 →	+4.014	+4.969	.008	.008	1	3
BLOOD_Lymphoma	IPO4 →	+4.429	+5.247	.005	.005	1	3
BLOOD_Lymphoma	PALB2 →	+4.429	+5.247	.005	.005	1	3
BLOOD_Leukemia	CDK5RAP3 →	+4.309	+4.560	.007	.007	1	3
BLOOD_Leukemia	RYBP →	+5.894	+5.321	.002	.002	1	3
BLOOD_Leukemia	SCO2 →	+4.309	+4.560	.007	.007	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,883 associations by consensus.

TRAF7 by PILRA expression — BLOOD_Lymphoma

Explore this box plot interactively →