PIK3CG

Across TCGA patient cohorts, PIK3CG RNA expression is significantly associated with the protein abundance of many other proteins, with 22,733 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PIK3CG-associated proteins across cancer lineages are TBC1D2B, ARHGEF6_S225, and PTPN7. Each is linked with PIK3CG in more than 9 cancer types. Because this analysis shows association rather than direction, both PIK3CG-to-partner and partner-to-PIK3CG results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PIK3CG versus TBC1D2B in GBM, with a Pearson correlation of 0.71.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PIK3CG→partner) and Y-score (partner→PIK3CG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TBC1D2B →	+0.427	+0.929	<.001	<.001	3	10
LSCC	ARHGEF6_S225 →	+0.829	+0.990	<.001	<.001	3	10
OV	PTPN7 →	+0.659	+0.999	<.001	<.001	3	10
LSCC	RASAL3 →	+0.606	+1.117	<.001	<.001	3	10
HNSC	RCSD1 →	+0.742	+1.084	<.001	<.001	3	10
GBM	SASH3 →	+0.665	+1.021	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,733 associations by consensus.

PIK3CG vs TBC1D2B — GBM

Explore this scatter interactively →