PIK3CG

Across TCGA patient cohorts, PIK3CG protein abundance is significantly associated with the RNA expression of many other genes, with 14,827 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PIK3CG-associated genes across cancer lineages are TLR8, IL10RA, and ARHGAP9. Each is linked with PIK3CG in more than 6 cancer types. Because this analysis shows association rather than direction, both PIK3CG-to-partner and partner-to-PIK3CG results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PIK3CG versus TLR8 in GBM, with a Pearson correlation of 0.70.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PIK3CG→partner) and Y-score (partner→PIK3CG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TLR8 →	+1.075	+0.570	<.001	<.001	3	7
GBM	IL10RA →	+1.306	+0.649	<.001	<.001	3	7
HNSC	ARHGAP9 →	+1.017	+0.570	<.001	<.001	3	7
GBM	DOCK2 →	+1.111	+0.649	<.001	<.001	3	7
UCEC	AOAH →	+1.316	+0.531	<.001	<.001	3	7
GBM	ITGAX →	+1.089	+0.545	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,827 associations by consensus.

PIK3CG vs TLR8 — GBM

Explore this scatter interactively →