PIK3CDP1

Across TCGA patient cohorts, PIK3CDP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,218 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PIK3CDP1-associated GO terms across cancer lineages are Regulation of mitochondrial gene expression, Positive regulation of proteasomal protein catabolic process, and Ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway. Each is linked with PIK3CDP1 in more than 9 cancer types. Because this analysis shows association rather than direction, both PIK3CDP1-to-partner and partner-to-PIK3CDP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mitochondrial gene expression grouped by PIK3CDP1-low versus PIK3CDP1-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PIK3CDP1→partner) and Y-score (partner→PIK3CDP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Regulation of mitochondrial gene expression →	+0.071	+0.039	<.001	.001	3	10
STAD	Positive regulation of proteasomal protein catabolic process →	+0.070	+0.066	<.001	<.001	3	9
STAD	Ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway →	+0.067	+0.067	<.001	<.001	3	9
STAD	Vesicle localization →	+0.064	+0.071	<.001	<.001	3	9
STAD	Regulation of organelle assembly →	+0.070	+0.072	<.001	<.001	3	9
STAD	Positive regulation of protein modification by small protein conjugation or removal →	+0.074	+0.070	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,218 associations by consensus.

Regulation of mitochondrial gene expression by PIK3CDP1 expression — ESCA

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