PIK3CB

Across TCGA patient cohorts, PIK3CB RNA expression is significantly associated with the protein abundance of many other proteins, with 11,321 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible PIK3CB-associated proteins across cancer lineages are RSRC1, GMPS, and NCK1. Each is linked with PIK3CB in more than 5 cancer types. Because this analysis shows association rather than direction, both PIK3CB-to-partner and partner-to-PIK3CB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PIK3CB versus RSRC1 in UCEC, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PIK3CB→partner) and Y-score (partner→PIK3CB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RSRC1 →	+0.273	+0.438	.002	<.001	3	6
OV	GMPS →	+0.538	+0.609	.001	.008	3	5
OV	NCK1 →	+0.303	+0.718	.002	<.001	3	4
HNSC	CTPS2 →	+0.339	+0.636	<.001	<.001	3	4
OV	DBR1 →	+0.261	+0.712	<.001	<.001	3	4
UCEC	ABCF3 →	+0.212	+0.295	.002	.006	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,321 associations by consensus.

PIK3CB vs RSRC1 — UCEC

Explore this scatter interactively →