PIK3CB

Across TCGA patient cohorts, PIK3CB protein abundance is significantly associated with the RNA expression of many other genes, with 7,293 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible PIK3CB-associated genes across cancer lineages are CEP70, COPB2, and GAPDHP39. Each is linked with PIK3CB in more than 5 cancer types. Because this analysis shows association rather than direction, both PIK3CB-to-partner and partner-to-PIK3CB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PIK3CB versus CEP70 in LUAD, with a Pearson correlation of 0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PIK3CB→partner) and Y-score (partner→PIK3CB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CEP70 →	+0.893	+0.168	<.001	.003	3	6
OV	COPB2 →	+0.522	+0.274	<.001	.002	3	5
LUAD	GAPDHP39 →	+0.418	+0.167	<.001	<.001	3	5
CCRCC	EEF1A1P25 →	+0.514	+0.371	<.001	<.001	3	4
OV	RBP2 →	+0.884	+0.261	<.001	.004	3	3
LSCC	RNF7 →	+0.492	+0.258	.001	.001	2	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,293 associations by consensus.

PIK3CB vs CEP70 — LUAD

Explore this scatter interactively →