PIK3C3

Across TCGA patient cohorts, PIK3C3 protein abundance is significantly associated with the RNA expression of many other genes, with 9,315 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible PIK3C3-associated genes across cancer lineages are MARVELD2, FIG4, and LINC00943. Each is linked with PIK3C3 in more than 3 cancer types. Because this analysis shows association rather than direction, both PIK3C3-to-partner and partner-to-PIK3C3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PIK3C3 versus MARVELD2 in CCRCC, with a Pearson correlation of -0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PIK3C3→partner) and Y-score (partner→PIK3C3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	MARVELD2 →	-0.623	-0.099	.009	.006	3	4
OV	FIG4 →	+0.419	+0.170	<.001	.003	3	3
HNSC	LINC00943 →	+0.304	+0.099	.006	.001	3	3
HNSC	ME2 →	+0.437	+0.154	.009	.001	3	3
CCRCC	PPP1R13L →	-0.520	-0.087	<.001	<.001	3	3
UCEC	LINC01215 →	+0.658	+0.125	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,315 associations by consensus.

PIK3C3 vs MARVELD2 — CCRCC

Explore this scatter interactively →