PIK3C3

Across TCGA cell cohorts, PIK3C3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,229 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible PIK3C3-associated GO terms across cancer lineages are Regulation of protein lipidation, Positive regulation of protein lipidation, and Positive regulation of lipoprotein metabolic process. Each is linked with PIK3C3 in more than 11 cancer types. Because this analysis shows association rather than direction, both PIK3C3-to-partner and partner-to-PIK3C3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein lipidation grouped by PIK3C3-low versus PIK3C3-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PIK3C3→partner) and Y-score (partner→PIK3C3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Regulation of protein lipidation →	+0.122	+0.775	<.001	.001	3	12
LUNG_SCLC	Positive regulation of protein lipidation →	+0.148	+1.029	<.001	<.001	3	11
LUNG_SCLC	Positive regulation of lipoprotein metabolic process →	+0.148	+1.029	<.001	<.001	3	11
SOFT_TISSUE	Autophagy of peroxisome →	+0.079	+0.758	.001	<.001	2	11
SOFT_TISSUE	Pexophagy →	+0.079	+0.758	.001	<.001	2	11
STOMACH	Golgi organization →	+0.080	+0.821	.002	.003	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,229 associations by consensus.

Regulation of protein lipidation by PIK3C3 expression — STOMACH

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