PIK3C2B

Across TCGA patient cohorts, PIK3C2B protein abundance is significantly associated with the RNA expression of many other genes, with 23,509 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PIK3C2B-associated genes across cancer lineages are SLC26A9, SMURF2, and RASAL1. Each is linked with PIK3C2B in more than 3 cancer types. Because this analysis shows association rather than direction, both PIK3C2B-to-partner and partner-to-PIK3C2B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PIK3C2B versus SLC26A9 in PDAC, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PIK3C2B→partner) and Y-score (partner→PIK3C2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	SLC26A9 →	+1.418	+0.314	.001	<.001	3	4
PDAC	SMURF2 →	-0.484	-0.306	.001	<.001	3	3
GBM	RASAL1 →	+0.884	+0.351	.009	.005	3	3
OV	ZNF556 →	-0.712	-0.579	.002	<.001	3	3
BRCA	LCLAT1 →	-0.493	-0.190	.002	.006	3	3
HNSC	CHROMR →	-0.515	-0.229	.003	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 23,509 associations by consensus.

PIK3C2B vs SLC26A9 — PDAC

Explore this scatter interactively →