PIK3C2B

Across TCGA cell cohorts, PIK3C2B RNA expression is significantly associated with the go_rna of many other GO terms, with 5,914 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PIK3C2B-associated GO terms across cancer lineages are Copper ion export, Positive regulation of myoblast differentiation, and mRNA transcription. Each is linked with PIK3C2B in more than 15 cancer types. Because this analysis shows association rather than direction, both PIK3C2B-to-partner and partner-to-PIK3C2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Copper ion export grouped by PIK3C2B-low versus PIK3C2B-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PIK3C2B→partner) and Y-score (partner→PIK3C2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Copper ion export →	-0.232	-2.308	<.001	<.001	3	16
SOFT_TISSUE	Positive regulation of myoblast differentiation →	+0.140	+1.614	<.001	<.001	3	13
OESOPHAGUS	mRNA transcription →	+0.068	+1.287	.002	.001	3	13
SOFT_TISSUE	Negative regulation of mRNA catabolic process →	+0.067	+1.180	<.001	<.001	3	12
LUNG_NSCLC_LUSC	Viral transcription →	+0.131	+1.031	<.001	.007	3	12
LARGE_INTESTINE	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.139	+1.039	<.001	.002	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,914 associations by consensus.

Copper ion export by PIK3C2B expression — URINARY_TRACT

Explore this box plot interactively →