PIK3C2A

Across TCGA patient cohorts, PIK3C2A protein abundance is significantly associated with the RNA expression of many other genes, with 4,732 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PIK3C2A-associated genes across cancer lineages are GTF2H1, COPB1, and CTR9. Each is linked with PIK3C2A in more than 4 cancer types. Because this analysis shows association rather than direction, both PIK3C2A-to-partner and partner-to-PIK3C2A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PIK3C2A versus GTF2H1 in LSCC, with a Pearson correlation of 0.63.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PIK3C2A→partner) and Y-score (partner→PIK3C2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	GTF2H1 →	+0.449	+0.191	<.001	<.001	3	5
BRCA	COPB1 →	+0.545	+0.278	<.001	<.001	3	5
BRCA	CTR9 →	+0.567	+0.211	<.001	<.001	3	5
OV	C11orf58 →	+0.629	+0.314	<.001	<.001	3	4
LSCC	PSMA1 →	+0.716	+0.272	<.001	<.001	3	4
OV	SERGEF →	+0.624	+0.329	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,732 associations by consensus.

PIK3C2A vs GTF2H1 — LSCC

Explore this scatter interactively →