PIK3C2A

Across TCGA cell cohorts, PIK3C2A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,781 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PIK3C2A-associated GO terms across cancer lineages are Post-Golgi vesicle-mediated transport, Golgi to plasma membrane transport, and Telomere tethering at nuclear periphery. Each is linked with PIK3C2A in more than 16 cancer types. Because this analysis shows association rather than direction, both PIK3C2A-to-partner and partner-to-PIK3C2A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Post-Golgi vesicle-mediated transport grouped by PIK3C2A-low versus PIK3C2A-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PIK3C2A→partner) and Y-score (partner→PIK3C2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Post-Golgi vesicle-mediated transport →	+0.101	+1.414	<.001	.001	3	17
SKIN	Golgi to plasma membrane transport →	+0.077	+0.824	<.001	<.001	3	16
STOMACH	Telomere tethering at nuclear periphery →	+0.133	+0.954	.006	.007	3	16
UPPER_AERODIGESTIVE_TRACT	Golgi vesicle transport →	+0.062	+0.960	.007	.002	2	16
OESOPHAGUS	Vesicle-mediated transport to the plasma membrane →	+0.061	+0.969	.005	.004	2	16
STOMACH	Cytosolic transport →	+0.084	+1.076	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,781 associations by consensus.

Post-Golgi vesicle-mediated transport by PIK3C2A expression — OESOPHAGUS

Explore this box plot interactively →