PIH1D2

Across TCGA patient cohorts, PIH1D2 protein abundance is significantly associated with the RNA expression of many other genes, with 1,744 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PIH1D2-associated genes across cancer lineages are BIK, GMDS, and LRRC63. Each is linked with PIH1D2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PIH1D2-to-partner and partner-to-PIH1D2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PIH1D2 versus BIK in UCEC, with a Pearson correlation of 0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PIH1D2→partner) and Y-score (partner→PIH1D2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	BIK →	+1.386	+0.939	<.001	.003	3	2
LUAD	GMDS →	+0.798	+0.970	.001	.006	3	2
UCEC	LRRC63 →	+0.682	+0.900	.002	<.001	3	2
LUAD	CST4 →	+0.620	+0.750	.004	.001	3	1
LUAD	NFE2 →	-1.460	-1.013	<.001	.003	3	1
LUAD	BNIPL →	-2.195	-0.969	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,744 associations by consensus.

PIH1D2 vs BIK — UCEC

Explore this scatter interactively →