PIH1D2

Across TCGA patient cohorts, PIH1D2 mutation is significantly associated with the RNA expression of many other genes, with 50 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PIH1D2-associated genes across cancer lineages are BTG3P1, LYZL4, and OR51A7. Each is linked with PIH1D2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PIH1D2-to-partner and partner-to-PIH1D2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BTG3P1 grouped by PIH1D2-low versus PIH1D2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PIH1D2→partner) and Y-score (partner→PIH1D2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	BTG3P1 →	+0.089	+7.816	<.001	.008	3	1
UCEC	LYZL4 →	+0.339	+4.046	<.001	.003	3	1
UCEC	OR51A7 →	+0.175	+4.021	<.001	.001	3	1
SKCM	H2AB3 →	+0.109	+7.816	<.001	.008	3	1
LIHC	RNA5SP149 →	+0.422	+5.186	<.001	.007	3	1
LIHC	MSRB1P1 →	+0.151	+5.268	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 50 associations by consensus.

BTG3P1 by PIH1D2 expression — SKCM

Explore this box plot interactively →