PIGX

Across TCGA patient cohorts, PIGX RNA expression is significantly associated with the protein abundance of many other proteins, with 17,605 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PIGX-associated proteins across cancer lineages are PAK2, ATP11B, and ECT2_T359. Each is linked with PIGX in more than 5 cancer types. Because this analysis shows association rather than direction, both PIGX-to-partner and partner-to-PIGX results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PIGX versus PAK2 in OV, with a Pearson correlation of 0.62.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PIGX→partner) and Y-score (partner→PIGX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PAK2 →	+0.322	+0.672	<.001	<.001	3	6
HNSC	ATP11B →	+0.555	+1.116	<.001	<.001	3	5
HNSC	ECT2_T359 →	+1.175	+1.225	<.001	<.001	3	5
GBM	ABI3 →	-0.560	-0.432	<.001	<.001	3	5
OV	GMPS →	+0.713	+0.821	<.001	<.001	3	5
LSCC	VPS13C →	-0.292	-0.698	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,605 associations by consensus.

PIGX vs PAK2 — OV

Explore this scatter interactively →