PIGX

Across TCGA patient cohorts, PIGX protein abundance is significantly associated with the RNA expression of many other genes, with 8,148 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PIGX-associated genes across cancer lineages are LY86, CCR2, and CD180. Each is linked with PIGX in more than 2 cancer types. Because this analysis shows association rather than direction, both PIGX-to-partner and partner-to-PIGX results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PIGX versus LY86 in UCEC, with a Pearson correlation of -0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PIGX→partner) and Y-score (partner→PIGX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LY86 →	-0.929	-0.338	.002	.007	3	3
UCEC	CCR2 →	-0.933	-0.394	.004	.001	3	3
UCEC	CD180 →	-0.748	-0.396	.001	<.001	3	3
COAD	MZB1 →	-1.974	-0.248	.001	.009	3	3
UCEC	NCF1B →	-0.703	-0.401	.002	.002	3	3
UCEC	IGKV1-17 →	-1.840	-0.389	.008	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,148 associations by consensus.

PIGX vs LY86 — UCEC

Explore this scatter interactively →