PIGW

Across TCGA patient cohorts, PIGW protein abundance is significantly associated with the RNA expression of many other genes, with 3,294 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PIGW-associated genes across cancer lineages are SRSF6, HNRNPU, and HDHD5-AS1. Each is linked with PIGW in more than 1 cancer types. Because this analysis shows association rather than direction, both PIGW-to-partner and partner-to-PIGW results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PIGW versus SRSF6 in OV, with a Pearson correlation of 0.60.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PIGW→partner) and Y-score (partner→PIGW) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SRSF6 →	+0.774	+1.649	.001	.001	3	2
OV	HNRNPU →	+0.770	+1.504	.005	.006	3	2
GBM	HDHD5-AS1 →	+0.718	+0.628	<.001	<.001	3	2
OV	SNHG30 →	+0.978	+1.559	.004	.003	3	2
GBM	RSBN1 →	+0.495	+0.569	<.001	<.001	3	2
LSCC	FKTN →	+0.646	+0.682	.008	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,294 associations by consensus.

PIGW vs SRSF6 — OV

Explore this scatter interactively →