PIGW

Across TCGA cell cohorts, PIGW RNA expression is significantly associated with the go_rna of many other GO terms, with 3,759 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PIGW-associated GO terms across cancer lineages are Maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), Regulation of DNA replication, and Replication fork processing. Each is linked with PIGW in more than 16 cancer types. Because this analysis shows association rather than direction, both PIGW-to-partner and partner-to-PIGW results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) grouped by PIGW-low versus PIGW-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PIGW→partner) and Y-score (partner→PIGW) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.115	+0.897	<.001	<.001	3	17
PANCREAS	Regulation of DNA replication →	+0.066	+0.780	<.001	<.001	3	17
PANCREAS	Replication fork processing →	+0.133	+1.183	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Interstrand cross-link repair →	+0.095	+1.232	<.001	<.001	3	16
OESOPHAGUS	DNA-templated DNA replication →	+0.129	+1.004	.001	.002	3	16
OESOPHAGUS	DNA replication initiation →	+0.188	+1.212	<.001	.002	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,759 associations by consensus.

Maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) by PIGW expression — SOFT_TISSUE

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