PIGT

Across TCGA pan-cancer cohorts, PIGT Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated PIGT data layer compared with 25 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher PIGT Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated PIGT expression acts as an unfavorable survival marker, although some lineages such as BLCA show a favorable association.

STAD, SARC, and ESCA are the cancer types where PIGT Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	OS	Median	All	0.228	0.729	.010	24	view →
SARC	DFS	Median	All	0.121	0.611	.041	6	view →
ESCA	OS	Median	III,IV	0.130	0.574	.011	6	view →
BLCA	DFS	Median	All	1.000	0.608	.031	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

PIGT–STAD (OS)

Open the STAD breakdown →