PIGT

Across TCGA patient cohorts, PIGT protein abundance is significantly associated with the protein abundance of many other proteins, with 19,240 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PIGT-associated proteins across cancer lineages are APMAP, PIGS, and GPAA1. Each is linked with PIGT in more than 9 cancer types. Because this analysis shows association rather than direction, both PIGT-to-partner and partner-to-PIGT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PIGT versus APMAP in UCEC, with a Pearson correlation of 0.78.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PIGT→partner) and Y-score (partner→PIGT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	APMAP →	+0.522	+0.404	<.001	<.001	3	10
UCEC	PIGS →	+0.658	+0.634	<.001	<.001	3	10
UCEC	GPAA1 →	+0.859	+0.617	<.001	<.001	3	10
UCEC	PIGU →	+0.707	+0.549	<.001	<.001	3	10
UCEC	LMAN2L →	+0.671	+0.493	<.001	<.001	3	9
UCEC	MLEC →	+0.758	+0.437	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,240 associations by consensus.

PIGT vs APMAP — UCEC

Explore this scatter interactively →