Across TCGA pan-cancer cohorts, PIGQP1 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of PIGQP1’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where PIGQP1 RNA is repressed in tumor relative to normal tissue. In most cancer types PIGQP1 is over-expressed in tumor, although a few such as THCA and PRAD show the opposite, repressed pattern.

THCA, KICH, and PRAD are the cancer types where PIGQP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PIGQP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Female	II,III,IV	−0.636	<.001	10	view →
KICH	Female	All	+0.053	.035	2	view →
PRAD	All	All	−0.043	.003	2	view →
LUAD	Male	All	−0.063	.041	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: PIGQP1 RNA expression & survival · all PIGQP1 data types