PIGPP2

Across TCGA patient cohorts, PIGPP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,097 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PIGPP2-associated GO terms across cancer lineages are Negative regulation of binding, Retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum, and Positive regulation of cell growth. Each is linked with PIGPP2 in more than 6 cancer types. Because this analysis shows association rather than direction, both PIGPP2-to-partner and partner-to-PIGPP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of binding grouped by PIGPP2-low versus PIGPP2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PIGPP2→partner) and Y-score (partner→PIGPP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Negative regulation of binding →	+0.085	+0.128	<.001	<.001	3	7
STAD	Retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum →	+0.101	+0.128	<.001	<.001	3	6
STAD	Positive regulation of cell growth →	+0.079	+0.134	<.001	<.001	3	6
STAD	Protein-containing complex disassembly →	+0.089	+0.121	<.001	<.001	3	6
STAD	Monosaccharide metabolic process →	+0.088	+0.146	<.001	<.001	3	6
STAD	Protein transmembrane import into intracellular organelle →	+0.094	+0.121	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,097 associations by consensus.

Negative regulation of binding by PIGPP2 expression — STAD

Explore this box plot interactively →