PIGHP1

Across TCGA patient cohorts, PIGHP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,124 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible PIGHP1-associated GO terms across cancer lineages are Endocytic recycling, Mitotic G2 DNA damage checkpoint signaling, and Regulation of embryonic development. Each is linked with PIGHP1 in more than 30 cancer types. Because this analysis shows association rather than direction, both PIGHP1-to-partner and partner-to-PIGHP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endocytic recycling grouped by PIGHP1-low versus PIGHP1-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PIGHP1→partner) and Y-score (partner→PIGHP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Endocytic recycling →	+0.060	+0.578	<.001	<.001	3	31
STAD	Mitotic G2 DNA damage checkpoint signaling →	+0.062	+0.537	<.001	<.001	3	31
CHOL	Regulation of embryonic development →	+0.043	+0.553	<.001	.001	3	31
ESCA	Positive regulation of chromosome organization →	+0.077	+0.545	<.001	<.001	3	30
ESCA	Golgi vesicle transport →	+0.067	+0.523	.002	<.001	3	30
ESCA	Regulation of mRNA processing →	+0.075	+0.537	.002	<.001	3	30

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,124 associations by consensus.

Endocytic recycling by PIGHP1 expression — ESCA

Explore this box plot interactively →