PIGH

Across TCGA pan-cancer cohorts, PIGH mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated PIGH data layer compared with 18 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher PIGH mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated PIGH expression acts as an unfavorable survival marker.

CCRCC, PDAC, and LUAD are the cancer types where PIGH mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Median	III,IV	0.541	0.966	.005	22	view →
PDAC	OS	Quartile	All	0.383	0.732	.019	14	view →
LUAD	DFS	Quartile	II,III,IV	0.229	0.786	.013	9	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

PIGH–CCRCC (DFS)

Open the CCRCC breakdown →