PIGH

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PIGH mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PIGH-associated genes across cancer lineages are Adipocytes and Neurons. Each is linked with PIGH in more than 1 cancer types. Because this analysis shows association rather than direction, both PIGH-to-partner and partner-to-PIGH results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Adipocytes grouped by PIGH-low versus PIGH-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PIGH→partner) and Y-score (partner→PIGH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECAdipocytes →+0.032+2.336.001.03531
UCECNeurons →-0.026-3.148.011.02011
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Adipocytes by PIGH expression — UCEC

Box plot of Adipocytes in PIGH-low vs PIGH-high samples in UCEC.

Explore this box plot interactively →

Exploration