PIGH

Across TCGA cell cohorts, PIGH RNA expression is significantly associated with the go_rna of many other GO terms, with 3,474 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PIGH-associated GO terms across cancer lineages are Protein farnesylation, Regulation of translational fidelity, and Aminoacyl-tRNA metabolism involved in translational fidelity. Each is linked with PIGH in more than 8 cancer types. Because this analysis shows association rather than direction, both PIGH-to-partner and partner-to-PIGH results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein farnesylation grouped by PIGH-low versus PIGH-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PIGH→partner) and Y-score (partner→PIGH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Protein farnesylation →	+0.132	+0.414	<.001	<.001	3	9
SKIN	Regulation of translational fidelity →	+0.078	+0.488	<.001	<.001	3	9
SKIN	Aminoacyl-tRNA metabolism involved in translational fidelity →	+0.087	+0.448	<.001	<.001	3	9
LARGE_INTESTINE	Copper ion export →	-0.116	-0.437	.003	.008	2	9
OESOPHAGUS	Dolichol-linked oligosaccharide biosynthetic process →	+0.094	+1.171	<.001	.002	3	7
BLOOD_Myeloma	Protein catabolic process at synapse →	+0.137	+1.338	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,474 associations by consensus.

Protein farnesylation by PIGH expression — SKIN

Explore this box plot interactively →