phosphatidylinositol glycan anchor biosynthesis class F pseudogene 3Genealiases: []
Q-omics provides the consensus-scored PIGFP3 profile across patient tissues and cancer cell-line models. PIGFP3 expression is associated with patient survival in 11 of 34 cancer types, with the highest sampling consensus in READ. Among the 18 cancer types available for tumor–normal comparison, PIGFP3 is differentially expressed in 2, with the highest sampling consensus in KIRC. Additionally, PIGFP3 RNA expression shows 6,396 significant gene co-expression associations, with the highest sampling consensus in TGCT. Together, these results highlight READ, KIRC, and TGCT as cancer lineages where PIGFP3 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for PIGFP3 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes PIGFP3 survival associations across molecular data types. PIGFP3 RNA expression shows survival associations in the most cancer types (11). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible PIGFP3 RNA expression–survival associations across cancer types. High PIGFP3 expression shows unfavorable associations in READ, ESCA, KIRC, LUAD, SKCM and KIRP. The READ Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify READ as the clearest survival context for PIGFP3 RNA expression.
This table summarizes PIGFP3 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 2. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for PIGFP3. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. PIGFP3 shows lower tumor expression in KIRC and KIRP. The KIRC box plot shows higher PIGFP3 RNA expression in normal versus tumor tissue (log2 FC = −0.031, t-test p = .016).
This table shows molecular features associated with PIGFP3 in patient tissues and cancer cell lines. In patient samples, PIGFP3 shows the broadest associations at the RNA and protein expression levels, with TGCT recurring as the lineage with the largest associated feature set.
