PIGFP1

Across TCGA pan-cancer cohorts, PIGFP1 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated PIGFP1 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher PIGFP1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated PIGFP1 expression acts as an unfavorable survival marker, although some lineages such as PAAD and LAML show a favorable association.

HNSC, PAAD, and LIHC are the cancer types where PIGFP1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Quartile	III,IV	0.575	0.736	.009	47	view →
PAAD	OS	Median	II,III,IV	0.573	0.285	.001	38	view →
LIHC	OS	Quartile	All	0.611	0.804	<.001	37	view →
LAML	DFS	Median	All	0.485	0.277	.006	20	view →
UVM	OS	Tertile	III,IV	0.596	0.980	.025	18	view →
LUAD	DFS	Tertile	III,IV	0.294	0.535	.019	17	view →
BLCA	OS	Tertile	IV	0.542	0.318	.002	15	view →
UCS	OS	Tertile	IV	0.675	0.206	.024	12	view →
KIRC	DFS	Median	IV	0.260	0.458	.030	12	view →
CESC	DFS	Median	IV	0.291	0.662	.010	12	view →
KIRP	DFS	Quartile	II,III,IV	0.326	0.816	.043	10	view →
UCEC	DFS	Median	All	0.800	0.872	.017	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

PIGFP1–HNSC (DFS)

Open the HNSC breakdown →