PIGC

Across TCGA cell cohorts, PIGC RNA expression is significantly associated with the go_rna of many other GO terms, with 2,207 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PIGC-associated GO terms across cancer lineages are mRNA 3'-end processing, Regulation of CD8-positive, alpha-beta T cell differentiation, and Negative regulation of CD8-positive, alpha-beta T cell differentiation. Each is linked with PIGC in more than 8 cancer types. Because this analysis shows association rather than direction, both PIGC-to-partner and partner-to-PIGC results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mRNA 3'-end processing grouped by PIGC-low versus PIGC-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PIGC→partner) and Y-score (partner→PIGC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	mRNA 3'-end processing →	+0.063	+0.500	.002	.004	3	9
BLOOD_Leukemia	Regulation of CD8-positive, alpha-beta T cell differentiation →	+0.114	+0.428	<.001	<.001	3	7
LIVER	Negative regulation of CD8-positive, alpha-beta T cell differentiation →	+0.228	+1.268	<.001	<.001	3	7
UPPER_AERODIGESTIVE_TRACT	Establishment of protein localization to endoplasmic reticulum membrane →	+0.074	+0.692	.004	.005	3	7
BLOOD_Leukemia	Negative regulation of purine nucleotide biosynthetic process →	+0.058	+0.508	<.001	<.001	2	7
STOMACH	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.044	+0.418	.009	.008	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,207 associations by consensus.

mRNA 3'-end processing by PIGC expression — SKIN

Explore this box plot interactively →