PIEZO1P1

Across TCGA patient cohorts, PIEZO1P1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,916 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PIEZO1P1-associated GO terms across cancer lineages are Acetyl-CoA metabolic process, Regulation of protein ubiquitination, and Negative regulation of protein ubiquitination. Each is linked with PIEZO1P1 in more than 2 cancer types. Because this analysis shows association rather than direction, both PIEZO1P1-to-partner and partner-to-PIEZO1P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Acetyl-CoA metabolic process grouped by PIEZO1P1-low versus PIEZO1P1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PIEZO1P1→partner) and Y-score (partner→PIEZO1P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Acetyl-CoA metabolic process →	+0.066	+0.044	<.001	.001	3	3
STAD	Regulation of protein ubiquitination →	+0.080	+0.072	<.001	<.001	3	3
STAD	Negative regulation of protein ubiquitination →	+0.081	+0.072	<.001	<.001	3	3
STAD	Protein localization to cell surface →	+0.069	+0.058	<.001	.002	3	3
STAD	Mitotic G1/S transition checkpoint signaling →	+0.077	+0.055	<.001	.002	3	3
STAD	Protein-RNA complex disassembly →	+0.050	+0.079	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,916 associations by consensus.

Acetyl-CoA metabolic process by PIEZO1P1 expression — STAD

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