PICART1

Across TCGA pan-cancer cohorts, PICART1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated PICART1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher PICART1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated PICART1 expression acts as an unfavorable survival marker, although some lineages such as BLCA and SKCM show a favorable association.

KIRC, LUSC, and BLCA are the cancer types where PICART1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	II,III,IV	0.376	0.639	<.001	119	view →
LUSC	DFS	Quartile	All	0.322	0.530	.001	54	view →
BLCA	OS	Quartile	II,III,IV	0.787	0.633	.003	50	view →
SKCM	OS	Quartile	II,III,IV	0.915	0.774	<.001	43	view →
GBM	DFS	Median	All	0.206	0.305	.006	32	view →
LGG	DFS	Median	All	0.754	0.887	<.001	32	view →
UCEC	OS	Tertile	All	0.545	0.745	.004	32	view →
UVM	DFS	Median	All	0.295	0.858	.014	14	view →
OV	OS	Median	III,IV	0.272	0.349	.035	14	view →
PAAD	DFS	Median	II,III,IV	0.384	0.520	.022	13	view →
THYM	DFS	Quartile	II,III,IV	1.000	0.762	.011	12	view →
CESC	DFS	Quartile	All	0.610	0.802	.007	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

PICART1–KIRC (DFS)

Open the KIRC breakdown →