PIANP

Across TCGA pan-cancer cohorts, PIANP Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated PIANP data layer compared with 26 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher PIANP Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated PIANP expression acts as an unfavorable survival marker.

LUAD, BLCA, and STAD are the cancer types where PIANP Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	All	0.272	0.814	<.001	42	view →
BLCA	DFS	Median	All	0.180	0.629	<.001	36	view →
STAD	OS	Median	II,III,IV	0.183	0.677	.004	24	view →
COAD	OS	Median	II,III,IV	0.556	0.850	.042	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

PIANP–LUAD (OS)

Open the LUAD breakdown →