PIANP

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PIANP RNA expression is significantly associated with the protein abundance of many other proteins, with 13,985 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PIANP-associated proteins across cancer lineages are SARM1, AGO1, and NEO1. Each is linked with PIANP in more than 4 cancer types. Because this analysis shows association rather than direction, both PIANP-to-partner and partner-to-PIANP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PIANP versus SARM1 in UCEC, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PIANP→partner) and Y-score (partner→PIANP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECSARM1 →+0.424+0.655<.001.00435
UCECAGO1 →+0.330+0.899<.001<.00135
UCECNEO1 →+0.537+0.953<.001<.00134
GBMPADI4 →-1.068-0.575<.001.00334
UCECPALM →+0.595+0.819<.001<.00134
PDACSSR3_S105 →-0.774-0.247<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 13,985 associations by consensus.

PIANP vs SARM1 — UCEC

Per-sample scatter of PIANP vs SARM1 in UCEC (Pearson r = 0.36).

Explore this scatter interactively →

Exploration