PIANP

Across TCGA patient cohorts, PIANP protein abundance is significantly associated with the protein abundance of many other proteins, with 5,939 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PIANP-associated proteins across cancer lineages are ARPC1B, ARPC5, and ARPC5L_S64. Each is linked with PIANP in more than 1 cancer types. Because this analysis shows association rather than direction, both PIANP-to-partner and partner-to-PIANP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PIANP versus ARPC1B in GBM, with a Pearson correlation of -0.57.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PIANP→partner) and Y-score (partner→PIANP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ARPC1B →	-0.579	-0.574	<.001	<.001	3	1
GBM	ARPC5 →	-0.283	-0.517	<.001	<.001	3	1
GBM	ARPC5L_S64 →	+0.386	+0.326	.001	.005	3	1
GBM	ARPP19 →	+0.285	+0.534	.001	<.001	3	1
GBM	ARPP21 →	+0.555	+0.416	<.001	<.001	3	1
GBM	ARPP21_S258 →	+0.690	+0.476	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,939 associations by consensus.

PIANP vs ARPC1B — GBM

Explore this scatter interactively →