PIANP

Across TCGA cell cohorts, PIANP RNA expression is significantly associated with the go_rna of many other GO terms, with 3,517 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PIANP-associated GO terms across cancer lineages are Thigmotaxis, Protein-DNA complex organization, and Transcription initiation at RNA polymerase II promoter. Each is linked with PIANP in more than 11 cancer types. Because this analysis shows association rather than direction, both PIANP-to-partner and partner-to-PIANP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Thigmotaxis grouped by PIANP-low versus PIANP-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PIANP→partner) and Y-score (partner→PIANP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Thigmotaxis →	+0.312	+0.847	.007	.001	3	12
BONE	Protein-DNA complex organization →	+0.071	+1.673	.002	.001	3	12
SKIN	Transcription initiation at RNA polymerase II promoter →	+0.053	+0.868	<.001	<.001	3	12
BLOOD_Leukemia	Regulation of cell cycle G1/S phase transition →	+0.070	+0.627	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Regulation of G1/S transition of mitotic cell cycle →	+0.066	+0.379	<.001	.006	3	12
OVARY	Positive regulation of double-strand break repair →	+0.085	+1.998	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,517 associations by consensus.

Thigmotaxis by PIANP expression — OESOPHAGUS

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