PI4KAP1

Across TCGA patient cohorts, PI4KAP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,105 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible PI4KAP1-associated GO terms across cancer lineages are RNA export from nucleus, mRNA export from nucleus, and Macromolecule deacylation. Each is linked with PI4KAP1 in more than 27 cancer types. Because this analysis shows association rather than direction, both PI4KAP1-to-partner and partner-to-PI4KAP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA export from nucleus grouped by PI4KAP1-low versus PI4KAP1-high in UVM.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PI4KAP1→partner) and Y-score (partner→PI4KAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UVM	RNA export from nucleus →	+0.062	+0.832	<.001	<.001	3	27
UVM	mRNA export from nucleus →	+0.062	+0.820	<.001	<.001	3	27
UVM	Macromolecule deacylation →	+0.046	+0.774	<.001	<.001	3	26
KIRP	Positive regulation of double-strand break repair →	+0.042	+0.967	<.001	<.001	3	26
UVM	mRNA transport →	+0.059	+0.823	<.001	<.001	3	26
UVM	Peptidyl-lysine acetylation →	+0.063	+0.980	<.001	<.001	3	26

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,105 associations by consensus.

RNA export from nucleus by PI4KAP1 expression — UVM

Explore this box plot interactively →