PI4K2B

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PI4K2B protein abundance is significantly associated with the RNA expression of many other genes, with 9,579 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PI4K2B-associated genes across cancer lineages are ZNF333, BTBD8, and FSD1. Each is linked with PI4K2B in more than 2 cancer types. Because this analysis shows association rather than direction, both PI4K2B-to-partner and partner-to-PI4K2B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PI4K2B versus ZNF333 in OV, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PI4K2B→partner) and Y-score (partner→PI4K2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVZNF333 →-0.502-0.246.004.00333
GBMBTBD8 →-0.576-0.294.001<.00133
GBMFSD1 →-0.963-0.357<.001<.00133
BRCAMPDZ →-0.669-0.295<.001<.00133
GBMMYH3 →-0.443-0.331<.001<.00133
GBMSTMN1 →-0.898-0.340.006.00233
Each partner links to its Q-omics profile. Showing the 6 strongest of 9,579 associations by consensus.

PI4K2B vs ZNF333 — OV

Per-sample scatter of PI4K2B vs ZNF333 in OV (Pearson r = -0.34).

Explore this scatter interactively →

Exploration