PI4K2B

Across TCGA patient cohorts, PI4K2B mutation is significantly associated with the RNA expression of many other genes, with 2,606 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PI4K2B-associated genes across cancer lineages are RNU6-1213P, RNU6-738P, and BIRC8. Each is linked with PI4K2B in more than 2 cancer types. Because this analysis shows association rather than direction, both PI4K2B-to-partner and partner-to-PI4K2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1213P grouped by PI4K2B-low versus PI4K2B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PI4K2B→partner) and Y-score (partner→PI4K2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-1213P →	+0.200	+3.654	<.001	.001	3	3
SKCM	RNU6-738P →	+0.164	+4.475	<.001	.005	3	3
COAD	BIRC8 →	+0.248	+4.516	<.001	.009	3	2
BLCA	OR2AI1P →	+0.103	+5.685	.005	.003	3	2
UCEC	MIR7702 →	+0.214	+4.153	<.001	.005	3	2
UCEC	RNA5SP478 →	+0.116	+3.829	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,606 associations by consensus.

RNU6-1213P by PI4K2B expression — UCEC

Explore this box plot interactively →