PI16

Across TCGA patient cohorts, PI16 protein abundance is significantly associated with the RNA expression of many other genes, with 11,120 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PI16-associated genes across cancer lineages are RHOJ, ABCA8, and MAMDC2. Each is linked with PI16 in more than 6 cancer types. Because this analysis shows association rather than direction, both PI16-to-partner and partner-to-PI16 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PI16 versus RHOJ in OV, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PI16→partner) and Y-score (partner→PI16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	RHOJ →	+0.958	+0.830	<.001	<.001	3	7
OV	ABCA8 →	+1.362	+0.878	<.001	<.001	3	7
UCEC	MAMDC2 →	+1.321	+0.427	<.001	.001	3	7
HNSC	ATP1A2 →	+1.558	+0.512	<.001	<.001	3	7
BRCA	PLAC9 →	+0.952	+0.599	<.001	<.001	3	7
UCEC	ASPA →	+0.711	+0.451	.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,120 associations by consensus.

PI16 vs RHOJ — OV

Explore this scatter interactively →