PI15

Across TCGA patient cohorts, PI15 protein abundance is significantly associated with the RNA expression of many other genes, with 7,359 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PI15-associated genes across cancer lineages are SCN1B, CSMD2, and LOXL2. Each is linked with PI15 in more than 2 cancer types. Because this analysis shows association rather than direction, both PI15-to-partner and partner-to-PI15 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PI15 versus SCN1B in LUAD, with a Pearson correlation of 0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PI15→partner) and Y-score (partner→PI15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	SCN1B →	+0.577	+0.603	<.001	<.001	3	3
LSCC	CSMD2 →	+0.631	+0.814	<.001	<.001	3	3
LSCC	LOXL2 →	+0.962	+0.695	<.001	<.001	3	3
LUAD	FKBP10 →	+1.053	+0.529	<.001	<.001	3	3
HNSC	VEGFC →	+1.601	+0.455	<.001	.001	3	3
LUAD	ITGA5 →	+0.846	+0.695	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,359 associations by consensus.

PI15 vs SCN1B — LUAD

Explore this scatter interactively →