PI15

Across TCGA patient cohorts, PI15 protein abundance is significantly associated with the protein abundance of many other proteins, with 21,824 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PI15-associated proteins across cancer lineages are FTH1_S183, PHLDB2_S204, and CTSB. Each is linked with PI15 in more than 3 cancer types. Because this analysis shows association rather than direction, both PI15-to-partner and partner-to-PI15 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PI15 versus FTH1_S183 in HNSC, with a Pearson correlation of 0.49.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PI15→partner) and Y-score (partner→PI15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	FTH1_S183 →	+0.876	+0.463	<.001	<.001	3	4
LUAD	PHLDB2_S204 →	+0.612	+0.633	<.001	<.001	3	3
LSCC	CTSB →	+0.358	+0.774	.001	<.001	3	3
HNSC	DHX8_S460 →	-0.401	-0.467	<.001	<.001	3	3
HNSC	ESCO2_S75 →	-0.984	-0.469	<.001	.001	3	3
HNSC	FEN1 →	-0.576	-0.513	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,824 associations by consensus.

PI15 vs FTH1_S183 — HNSC

Explore this scatter interactively →