PHYKPL

Across TCGA patient cohorts, PHYKPL mutation is significantly associated with the RNA expression of many other genes, with 1,842 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PHYKPL-associated genes across cancer lineages are RNU6-1214P, OR5I1, and OFD1P5Y. Each is linked with PHYKPL in more than 2 cancer types. Because this analysis shows association rather than direction, both PHYKPL-to-partner and partner-to-PHYKPL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1214P grouped by PHYKPL-low versus PHYKPL-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PHYKPL→partner) and Y-score (partner→PHYKPL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU6-1214P →	+0.664	+4.516	.001	.009	3	3
LUAD	OR5I1 →	+0.054	+7.930	<.001	.008	3	2
LUAD	OFD1P5Y →	+0.019	+7.930	<.001	.008	3	2
COAD	RNU6-927P →	+0.706	+5.602	<.001	<.001	3	2
CESC	MIR4446 →	+0.508	+5.010	<.001	.009	3	2
BRCA	SNRPCP20 →	+0.230	+5.045	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,842 associations by consensus.

RNU6-1214P by PHYKPL expression — COAD

Explore this box plot interactively →