PHYHD1

Across TCGA pan-cancer cohorts, PHYHD1 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated PHYHD1 data layer compared with 24 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher PHYHD1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated PHYHD1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and PDAC show a favorable association.

CCRCC, PDAC, and GBM are the cancer types where PHYHD1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Tertile	All	1.000	0.649	.007	19	view →
PDAC	DFS	Tertile	III,IV	0.900	0.262	.002	15	view →
GBM	DFS	Median	All	0.648	0.838	.032	1	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

PHYHD1–CCRCC (OS)

Open the CCRCC breakdown →