PHTF2

Across TCGA cell cohorts, PHTF2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,415 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PHTF2-associated GO terms across cancer lineages are Peptidyl-glutamic acid carboxylation, Protein carboxylation, and DNA synthesis involved in DNA repair. Each is linked with PHTF2 in more than 12 cancer types. Because this analysis shows association rather than direction, both PHTF2-to-partner and partner-to-PHTF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Peptidyl-glutamic acid carboxylation grouped by PHTF2-low versus PHTF2-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PHTF2→partner) and Y-score (partner→PHTF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Peptidyl-glutamic acid carboxylation →	+0.131	+0.863	<.001	.001	3	13
OVARY	Protein carboxylation →	+0.131	+0.863	<.001	.001	3	13
LUNG_NSCLC_LUSC	DNA synthesis involved in DNA repair →	+0.096	+1.032	.001	.006	3	12
SKIN	Regulation of sister chromatid segregation →	+0.074	+0.701	<.001	.001	2	13
BREAST	Cell division →	+0.103	+1.106	<.001	<.001	3	12
STOMACH	Regulation of metaphase/anaphase transition of cell cycle →	+0.115	+1.099	<.001	.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,415 associations by consensus.

Peptidyl-glutamic acid carboxylation by PHTF2 expression — OVARY

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